Reductant?Free Cross?Electrophile Synthesis of Di(hetero)arylmethanes by Palladium?Catalyzed Desulfinative C?C Coupling

An efficient Pd-catalyzed one-pot desulfinative cross-coupling to access medicinally relevant di(hetero)arylmethanes is reported. The method reductant-free, and involves a sulfinate transfer reagent Pd-catalyst mediating the union of two electrophilic coupling partners; (hetero)aryl halide benzyl halide. We establish for first time that sulfinates, generated in situ, undergo with halides generate di(hetero)arylmethanes. reaction can be extended benzylic pseudohalides derived from alcohols.The reactions are straightforward perform scalable, all components commercially available.